Pure TMG
Pure TMG

Pure TMG

Cellular Health

€29,95

Trimethylglycine (TMG) plays a key role in methylation, a biological process involved in gene regulation, DNA stability, metabolic function, and cellular maintenance. As a primary methyl donor, TMG contributes to the body's natural methylation pathways, which support normal physiological function and cellular homeostasis.

The purity of Manapura®'s TMG is guaranteed, and like every batch of our products, it is tested by third-parties to ensure a consistently high level of purity.
  • Homeostasis
  • Heart Health
  • Insulin Support
  • Anti-Inflammatory
  • Sleep Aid
  • Fitness

One-time

€29,95

The purity of Manapura's TMG is guaranteed, and like every batch of all our longevity products, it is tested by third-parties to ensure a consistently high level of purity.

Contains 60 capsules. One capsule contains 500mg of Pure TMG.

The capsule shell is made from 100% vegetable cellulose.

  • Vegan and Vegetarian friendly.
  • Gluten Free.

Manapura's current batch of Pure TMG has been third-party tested by an independant laboratory, and shown to be 99.62% pure.

Testing certificates for all our Longevity products are available upon request.

For maximum effectiveness, take two capsules daily with water.

Although TMG is effective any time of day, some studies suggest it may support sleep, making it an ideal choice for evening use.

UK Orders 

  • Standard Delivery: Processed in 1–2 business days, delivered within 2 days.
  • Express Delivery: Processed in 1 business day, delivered next working day.
    During busy periods, processing may take slightly longer.

International Orders 

  • Processed within 2 business days.
  • Delivery takes 7–14 business days, depending on local customs.
    Customs duties vary by country and are the customer’s responsibility.

Carriers 

  • UK: Royal Mail Tracked48 (standard) or Royal Mail Express (next-day).
  • North America, EU, Asia Pacific: Shipped via Royal Mail, then passed to a local carrier. You’ll receive tracking once your order is dispatched.
Pure TMG
€29,95

Our high-strength TMG capsules deliver a pure, bioavailable dose of this important nutrient, designed to support key cellular and metabolic functions.

TMG, also known as Betaine Anhydrous, is a naturally occurring compound found in foods like spinach, beets, shellfish, and whole grains.

TMG plays a key role in methylation — a core biochemical process involved in gene expression, DNA stability, and overall cellular health. As one of the body’s primary methyl donors, TMG contributes to overall cellular harmony and optimal function.

This supplement is a common component in wellness protocols aimed at supporting liver function, cellular energy production, and homocysteine balance. It is especially valued for its synergistic use with NMN, helping to support the body's natural NAD+ metabolism and energy systems.

Powerful Duo

TMG is commonly paired with NMN to support NAD+ pathways — helping optimise the body’s natural energy systems and cellular mechanisms.

Methylation Support

As a methyl donor, TMG can support essential cellular processes including gene regulation, neurotransmitter synthesis, and metabolism.

Quality Guaranteed

Our pure, clean supplement range is made in the UK under GMP standards and is third-party tested to ensure unmatched purity and safety in every batch.

Proven Research

Scientific studies have explored TMG’s role in supporting healthy homocysteine levels and metabolic function, highlighting its relevance in cellular wellness and nutritional science.

Ultimate NAD+ Trio

Supercharge your Sirtuins with Manapura’s Ultimate NAD+ set. Formulated to maximise DNA support, and save you 15%.

Shop now

NAD+ Duo

Boost DNA support with Manapura - curated NAD+ enhancement to promote healthier aging. Save 15% with our Pure NMN + TMG bundle.

Shop now
What are the benefits of TMG?

TMG has been shown to potentially support cardiovascular health, liver maintenance, and DNA methylation, key for cellular function.

 When should I take TMG?

Take 2 capsules per day with water.

Why is TMG often paired with NMN?

TMG acts as a methyl donor; a substance that donates a methyl (-CH3) group to other molecules. NMN increases NAD+ levels, and this process can be further optimised by increasing the levels of methyl donors in our body.

 Can TMG enhance physical performance?

Yes, studies have shown that TMG may support endurance and muscle recovery. For this reason it pairs well with not only NMN, but also Cordyceps.

 Is TMG safe?

TMG has been studied for cardiovascular health and is considered safe for healthy humans when used within recommended doses. Always consult your health practitioner if you are unsure about introducing new supplements to your routine.
What are the benefits of TMG?
When should I take TMG?
Why is TMG often paired with NMN?
Can TMG enhance physical performance?
Is TMG safe?

Meet our Advisors

Dr. Cherry Lo, Ph.D., is a researcher specialising in pathology and immunity, with degrees from CUHK and the University of Hong Kong. Her work focuses on the interaction between NK cells and rheumatoid arthritis, providing new insights into disease mechanisms. As a research scientist, she contributes to advancements in longevity science. With a passion for immunology and translational research, Dr. Lo is dedicated to uncovering innovative solutions for age-related diseases and immune health.

DR. CHERRY LO, Ph.D

Longevity Expert

READ INTERVIEW

Dr. Cherry Lo, Ph.D., is a researcher specialising in pathology and immunity, with degrees from CUHK and the University of Hong Kong. Her work focuses on the interaction between NK cells and rheumatoid arthritis, providing new insights into disease mechanisms. As a research scientist, she contributes to advancements in longevity science. With a passion for immunology and translational research, Dr. Lo is dedicated to uncovering innovative solutions for age-related diseases and immune health.

DR. CHERRY LO, Ph.D

Longevity Expert

Ben is the founder and head grower at one of the UK’s leading fungi farms, where he cultivates a deep passion for mushroom cultivation and education. Since launching his farm in 2022, he has dedicated himself to exploring fungi’s medicinal and ecological potential. Ben is a regular speaker at functional mushroom conferences around the UK where he shares his knowledge and enthusiasm for the fungal kingdom. He aims to inspire others to connect with these fascinating organisms.

BEN GIBSON

Mycology Expert

Ben is the founder and head grower at one of the UK’s leading fungi farms, where he cultivates a deep passion for mushroom cultivation and education. Since launching his farm in 2022, he has dedicated himself to exploring fungi’s medicinal and ecological potential. Ben is a regular speaker at functional mushroom conferences around the UK where he shares his knowledge and enthusiasm for the fungal kingdom. He aims to inspire others to connect with these fascinating organisms.

BEN GIBSON

Mycology Expert

Carolina is a holistic sleep coach specialising in circadian biology, nutritional therapy, and biohacking. With over seven years of experience, she blends scientific research with ancestral wisdom to help clients achieve deep, restorative sleep naturally. Her expertise in light exposure, stress resilience, and nervous system regulation allows her to create personalised, sustainable solutions without reliance on medication. Carolina is passionate about empowering individuals to optimise their sleep and overall well-being through evidence-based, holistic practices.

CAROLINA RAMUSKI

Sleep Expert

Carolina is a holistic sleep coach specialising in circadian biology, nutritional therapy, and biohacking. With over seven years of experience, she blends scientific research with ancestral wisdom to help clients achieve deep, restorative sleep naturally. Her expertise in light exposure, stress resilience, and nervous system regulation allows her to create personalised, sustainable solutions without reliance on medication. Carolina is passionate about empowering individuals to optimise their sleep and overall well-being through evidence-based, holistic practices.

CAROLINA RAMUSKI

Sleep Expert