Designed for Radiance: deeper detox, cellular renewal, and a smoother, balanced metabolic flow.

A powerful detox stack featuring Spermidine, Fisetin, Berberine, Reishi and Trans-Resveratrol.

Detox Stack

Cleanse & Reset

Save 40%

£157.80 £263.00

BLACK FRIDAY EXCLUSIVE

The Detox Bundle brings together Spermidine, Fisetin, Berberine, Reishi and Trans-Resveratrol to support natural liver detox, cellular clean-up, metabolic balance and everyday resilience.

Supports Natural Liver DetoxHelps Clear Out Old CellsSupports the bodies natural balancesProvides Strong Antioxidant DefencesMay Reduce Sluggish, Heavy Feelings

One-time

£157.80

Manapura specialises in clean, science-led supplement stacks for real-world results.

Ultra pure, high-grade ingredients onlyOnly the most natural production methodsA perfectly paired stack for stronger impactThird-party tested in certified labsLab-grade, UV safe amber glass vessel

Fisetin:

For maximum effectiveness, take one capsule daily with a meal for optimal absorption. For best results, complement your routine with a balanced diet rich in healthy fats.

Berberine:

For maximum effectiveness, take one capsule daily with a meal for optimal absorption.

Spermidine:

For maximum effectiveness, take two capsules daily with a meal for optimal absorption. For best results, complement your routine with a balanced diet rich in healthy fats.

Pure Trans-Resveratrol:

For maximum effectiveness, take two capsules daily with a meal for optimal absorption. For best results, complement your routine with a balanced diet rich in healthy fats.

All 4 supplements can be taken at any time of day; however, taking them at the same time every day is recommended.

All Manapura products are proudly:

  • Vegan and Vegetarian
  • Non-GMO
  • Allergen Free
  • Halal / Kosher Friendly

Pure Trans-Resveratrol:

  • Contains 60 capsules.
  • One capsule contains 500mg of Pure Trans-Resveratrol*, naturally sourced from Japonica plant extract.
  • Research suggests that Trans-Resveratrol*, sourced from Japonica is highly bioavailable and effective, making it a superior choice for supplementation.
  • The capsule shell is made from 100% vegetable cellulose.

Pure Berberine:

  • Contains 60 capsules.
  • One capsule contains 500mg of 98% Pure Berberine, naturally sourced from Berberis Aristata plant extract.
  • Research suggests that Berberine sourced from Berberis Aristata is highly bioavailable and effective, making it a superior choice for supplementation.
  • The capsule shell is made from 100% vegetable cellulose.

Pure Fisetin:

  • Contains 60 capsules.
  • One capsule contains 400mg of pure Fisetin*.
  • The capsule shell is made from 100% vegetable cellulose.

Pure Spermidine:

  • Contains 60 capsules.
  • One capsule contains 350mg of natural Spermidine-rich wheat germ extract.
  • The capsule shell is made from 100% vegetable cellulose.
  • PLEASE NOTE: CONTAINS GLUTEN

Organic Reishi:

  • Contains 50ml of dual liquid extract from the fruiting body of Reishi mushrooms, water, and organic ethanol (25% ABV).
  • Note this product contains Alcohol.

This product is intended for use by healthy adults only. Do not take if you are pregnant or breastfeeding.

For best results, complement your supplement routine with a balanced diet. Always consult with your doctor or healthcare professional before beginning any supplement, and never exceed the recommended daily dose.

Specifically regarding Fisetin:

Do not take if you are pregnant, breastfeeding, or using anticoagulant or antiplatelet medications—for example, warfarin (Coumadin), heparin, aspirin, or clopidogrel (Plavix)—which are typically prescribed to individuals with cardiovascular or clotting concerns.

UK ORDERS:

  • Standard Delivery (FREE):Delivered via Royal Mail 48H service.
  • Express Delivery (£3.95): Delivered via Royal Mail 24H service..

INTERNATIONAL ORDERS:

  • Standard Delivery (FREE): Delivered via Fedex Economy Services, 3-7 days.
  • Express Delivery (£3.95): Delivered via Fedex Prioirty Services, 2-4 days.

We are proud to cover customs, duties and taxes for our international customers.

Detox Stack
£157.80 £263.00

Ultra Pure

Extracted naturally - absolutely no synthetic additives or fillers

Medical Grade

We make our supplements in certified facilities (cGMP & ISO 9001) the same standards used for best-in-class pharmaceuticals.

Micronised For Maximum Absorption

Our capsule compounds are processed into tiny particles (micronised) so your body can absorb it more easily.

Vegan & Gluten-Free

Purposefully suitable for most diets, our zero-tolerance for additives gives you the cleanest forms that the body recognises and can absorb.

Manapura® VS Most Brands On The Market

Every single batch is tested by third-party labs.

Batch tested for heavy metals, toxins, and unwanted contaminants. Nothing gets shipped unless it meets the highest safety standards.

Detox Stack Supplement FAQs

What are the benefits of TMG?

TMG has been shown to potentially support cardiovascular health, liver maintenance, and DNA methylation, key for cellular function.

Can Berberine help with weight loss?

Yes! It activates AMPK, a metabolic enzyme that can help regulate fat storage and energy balance.

What form of Reishi is best — capsule, powder, or tincture?

Tinctures like Manapura’s offer faster absorption and higher bioavailability due to dual extraction methods.

What’s the optimal daily dosage of Berberine?

The most studied dosage is 500 mg, 2–3 times per day (totaling 1000–1500 mg/day), split between meals for best results.

How should I take Trans-Resveratrol?

Take 2 capsules daily with a source of fat, such as nuts or avocado, for optimal absorption.

What are the benefits of TMG?
Can Berberine help with weight loss?
What form of Reishi is best — capsule, powder, or tincture?
What’s the optimal daily dosage of Berberine?
How should I take Trans-Resveratrol?

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Meet our Advisors

Dr. Cherry Lo, Ph.D., is a researcher specialising in pathology and immunity, with degrees from CUHK and the University of Hong Kong. Her work focuses on the interaction between NK cells and rheumatoid arthritis, providing new insights into disease mechanisms. As a research scientist, she contributes to advancements in longevity science. With a passion for immunology and translational research, Dr. Lo is dedicated to uncovering innovative solutions for age-related diseases and immune health.

DR. CHERRY LO, Ph.D

Longevity Expert

READ INTERVIEW

Dr. Cherry Lo, Ph.D., is a researcher specialising in pathology and immunity, with degrees from CUHK and the University of Hong Kong. Her work focuses on the interaction between NK cells and rheumatoid arthritis, providing new insights into disease mechanisms. As a research scientist, she contributes to advancements in longevity science. With a passion for immunology and translational research, Dr. Lo is dedicated to uncovering innovative solutions for age-related diseases and immune health.

DR. CHERRY LO, Ph.D

Longevity Expert

Ben is the founder and head grower at one of the UK’s leading fungi farms, where he cultivates a deep passion for mushroom cultivation and education. Since launching his farm in 2022, he has dedicated himself to exploring fungi’s medicinal and ecological potential. Ben is a regular speaker at functional mushroom conferences around the UK where he shares his knowledge and enthusiasm for the fungal kingdom. He aims to inspire others to connect with these fascinating organisms.

BEN GIBSON

Mycology Expert

Ben is the founder and head grower at one of the UK’s leading fungi farms, where he cultivates a deep passion for mushroom cultivation and education. Since launching his farm in 2022, he has dedicated himself to exploring fungi’s medicinal and ecological potential. Ben is a regular speaker at functional mushroom conferences around the UK where he shares his knowledge and enthusiasm for the fungal kingdom. He aims to inspire others to connect with these fascinating organisms.

BEN GIBSON

Mycology Expert

Carolina is a holistic sleep coach specialising in circadian biology, nutritional therapy, and biohacking. With over seven years of experience, she blends scientific research with ancestral wisdom to help clients achieve deep, restorative sleep naturally. Her expertise in light exposure, stress resilience, and nervous system regulation allows her to create personalised, sustainable solutions without reliance on medication. Carolina is passionate about empowering individuals to optimise their sleep and overall well-being through evidence-based, holistic practices.

CAROLINA RAMUSKI

Sleep Expert

Carolina is a holistic sleep coach specialising in circadian biology, nutritional therapy, and biohacking. With over seven years of experience, she blends scientific research with ancestral wisdom to help clients achieve deep, restorative sleep naturally. Her expertise in light exposure, stress resilience, and nervous system regulation allows her to create personalised, sustainable solutions without reliance on medication. Carolina is passionate about empowering individuals to optimise their sleep and overall well-being through evidence-based, holistic practices.

CAROLINA RAMUSKI

Sleep Expert