Manapura delivers high-strength natural spermidine capsules, Supporting healthy ageing and autophagy, the body’s natural cellular clean-up process.

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Natural Spermidine

Cellular Health

Save 30%

£31.50 £45.00

Manapura Natural Spermidine supplement helps your cells renew and recycle themselves, supporting healthy aging, heart & brain health and everyday energy.

Supports autophagy, your body's cellular clean-up processSupports brain function & mental claritySupports heart & cardiovascular healthSupports healthy hair & skinPromotes healthy ageing & longevity

One-time

£31.50
SAVE 40% ON SETS - BLACK FRIDAY SALE
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Cellular Repair Stack

Manapura specialises in pharmaceutical-grade potency for maximum benefit.

Naturally sourced from Wheat GermUltra high 10mg daily doseMicronised for maximum absorbencyLab-grade, UV safe amber glass vessel

Long term supplementation is linked to longer lifespan in multiple studies.

For maximum effectiveness, take two capsules daily with a meal for optimal absorption. For best results, complement your routine with a balanced diet rich in healthy fats.

Spermidine can be taken at any time of day; however, taking it at the same time every day is recommended.

Contains 60 capsules. One capsule contains 350mg of Spermidine-rich natural Wheatgerm Extract.

The capsule shell is made from 100% vegetable cellulose.

  • NOTE: CONTAINS GLUTEN
  • Vegan and Vegetarian
  • Non-GMO
  • Allergen Free
  • Halal / Kosher Friendly

This product is intended for use by healthy adults only. Do not take if you are pregnant or breastfeeding. Our Spermidine is produced from wheat germ extract, and therefore contains gluten. It is not suitable for individuals with celiac disease or gluten intolerance.

For best results, complement your supplement routine with a balanced diet. Always consult with your doctor or healthcare professional before beginning any supplement, and never exceed the recommended daily dose.

UK ORDERS:

  • Standard Delivery (FREE):Delivered via Royal Mail 48H service.
  • Express Delivery (£3.95): Delivered via Royal Mail 24H service..

INTERNATIONAL ORDERS:

  • Standard Delivery (FREE): Delivered via Fedex Economy Services, 3-7 days.
  • Express Delivery (£3.95): Delivered via Fedex Prioirty Services, 2-4 days.

We are proud to cover customs, duties and taxes for our international customers.
Natural Spermidine
£31.50 £45.00

We didn’t just make another Spermidine supplement.

We made it better, purer, cleaner, and designed to actually work for your body. Here's how:

Ultra Pure

Extracted naturally from Wheat Germ with no synthetic additives.

Medical Grade

We make our supplements in certified facilities (cGMP & ISO 9001) the same standards used for best-in-class pharmaceuticals.

Micronised For Maximum Absorption

Our Spermidine is processed into tiny particles (micronised) so your body can absorb it more easily.

Vegan & Gluten-Free

Purposefully suitable for most diets, our zero-tolerance for additives gives you the cleanest form of Spermidine that the body recognises and can absorb.

Manapura® VS Most Brands On The Market

Natural Spermidine Supplement FAQs

What is Spermidine, and how does it work?

Spermidine is a natural polyamine that promotes autophagy, the body’s cellular renewal process.

 How long do I need to supplement for to achieve the benefits?

Long term supplementation is linked to longer lifespan in multiple studies.

 Can Spermidine improve longevity?

Yes, research suggests it supports healthy aging, brain function, and heart health.

 What is autophagy and why is it important?

Autophagy is the body’s natural clean-up process. It recycles dysfunctional cell components, supports energy efficiency, and protects against age-related disease.

 Does your Spermidine contain gluten?

Yes. This product is a natural wheatgerm extract, which contains Gluten, and so should not be taken if you are Gluten intolerant.

 Is Spermidine safe to take?

Yes, Spermidine is naturally found in the body and considered safe at recommended doses, although as noted above this product contains Gluten.

 How should I take Spermidine?

Take 2 capsules daily, preferably with a source of fat for enhanced absorption.
What is Spermidine, and how does it work?
How long do I need to supplement for to achieve the benefits?
Can Spermidine improve longevity?
What is autophagy and why is it important?
Does your Spermidine contain gluten?
Is Spermidine safe to take?
How should I take Spermidine?

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Meet our Advisors

Dr. Cherry Lo, Ph.D., is a researcher specialising in pathology and immunity, with degrees from CUHK and the University of Hong Kong. Her work focuses on the interaction between NK cells and rheumatoid arthritis, providing new insights into disease mechanisms. As a research scientist, she contributes to advancements in longevity science. With a passion for immunology and translational research, Dr. Lo is dedicated to uncovering innovative solutions for age-related diseases and immune health.

DR. CHERRY LO, Ph.D

Longevity Expert

READ INTERVIEW

Dr. Cherry Lo, Ph.D., is a researcher specialising in pathology and immunity, with degrees from CUHK and the University of Hong Kong. Her work focuses on the interaction between NK cells and rheumatoid arthritis, providing new insights into disease mechanisms. As a research scientist, she contributes to advancements in longevity science. With a passion for immunology and translational research, Dr. Lo is dedicated to uncovering innovative solutions for age-related diseases and immune health.

DR. CHERRY LO, Ph.D

Longevity Expert

Ben is the founder and head grower at one of the UK’s leading fungi farms, where he cultivates a deep passion for mushroom cultivation and education. Since launching his farm in 2022, he has dedicated himself to exploring fungi’s medicinal and ecological potential. Ben is a regular speaker at functional mushroom conferences around the UK where he shares his knowledge and enthusiasm for the fungal kingdom. He aims to inspire others to connect with these fascinating organisms.

BEN GIBSON

Mycology Expert

Ben is the founder and head grower at one of the UK’s leading fungi farms, where he cultivates a deep passion for mushroom cultivation and education. Since launching his farm in 2022, he has dedicated himself to exploring fungi’s medicinal and ecological potential. Ben is a regular speaker at functional mushroom conferences around the UK where he shares his knowledge and enthusiasm for the fungal kingdom. He aims to inspire others to connect with these fascinating organisms.

BEN GIBSON

Mycology Expert

Carolina is a holistic sleep coach specialising in circadian biology, nutritional therapy, and biohacking. With over seven years of experience, she blends scientific research with ancestral wisdom to help clients achieve deep, restorative sleep naturally. Her expertise in light exposure, stress resilience, and nervous system regulation allows her to create personalised, sustainable solutions without reliance on medication. Carolina is passionate about empowering individuals to optimise their sleep and overall well-being through evidence-based, holistic practices.

CAROLINA RAMUSKI

Sleep Expert

Carolina is a holistic sleep coach specialising in circadian biology, nutritional therapy, and biohacking. With over seven years of experience, she blends scientific research with ancestral wisdom to help clients achieve deep, restorative sleep naturally. Her expertise in light exposure, stress resilience, and nervous system regulation allows her to create personalised, sustainable solutions without reliance on medication. Carolina is passionate about empowering individuals to optimise their sleep and overall well-being through evidence-based, holistic practices.

CAROLINA RAMUSKI

Sleep Expert

Let customers speak for us

from 132 reviews

Resveratrol goes well with NMN. Taking both for 12 weeks and sleeping much better. Ive noticed not as many aches and pains

Jenna
Pure Trans-Resveratrol

Nice product. I take Trans-res with NMN - very affective for NAD+ levels. Lovely packaging

Jenna
Pure Trans-Resveratrol

Ive been thinking about taking NMN for a while now and feeling very good after 6 weeks. Lots more energy. Lovely packaging as well

Anonymous
Pure NMN

Nice packaging, quick delivery

Holly A.
Pure Berberine

I LOVE this. Capsules nice and small, and delivery came really quick.

Holly A.
Pure Hyaluronic Acid

I was drawn to the natural slant that Manapura has towards longevity supplements, but what I was expecting was the awesome quality of the product packaging - from the jar itself right through to the box

Kim
Pure Trans-Resveratrol

Already noticed that I've lost weight since taking these 2 weeks ago

Kim R.
Pure Berberine

10/10

Lottie P.
Natural Spermidine
Most Potent Lion's Mane

Love it so far. I've been taking Lion's Mane for a couple of weeks and honestly, I feel much sharper and focused. It's not like coffee jitters, more like a clear head where I can actually get through my work without zoning out or getting distracted. Definitely a keeper for me.

Rezwana B.
Organic Lion's Mane
Most Potent Lion's Mane

I can honestly say that this gives me an instant focus, I am a very busy Mum, self-employed woman and having the ability to focus whilst also juggling home educating my children is a must!!

Gemma H.
Organic Lion's Mane
Organic Cordyceps

I have been seeking an organic product for a very long time, as somebody who is conscious about what is put into my body, Manaura ticks all the boxes for me! The purity, The Packaging, It's Origin, It's Potency! All exceed my expectations! I highly recommend

Gemma H.
Organic Cordyceps
Organic Reishi

Absolutely spot-on, I take one pipette in the evenings to settle me into relaxation if it has been a very hectic day. Sleep is extremely important to me and this gives me a full night sleep with no groggy feeling the next day.

Gemma H.
Organic Reishi
Most Potent Lion's Mane

Strong stuff - bought all 3 mushroom liquids, actually feel them working, will be buying again when they run out.

James W.
Organic Lion's Mane
Organic Lion's Mane

i bought the mushroom trio initially mostly for the cordyceps but having tried lion's mane gummies before i can vouch these are very different. These got me through a very large inbox after coming back from a 2 week hol - not as tasty granted but can feel a difference in focus for sure

Liam W.
Organic Lion's Mane
Pure Fisetin

Manapura Spermidine offers a solid dose at a fair price. After a few weeks, I've noticed clearer focus and steady energy. Knowing it supports autophagy and healthy ageing makes it feel like a smart, well-formulated addition to my routine. No side effects so far.

Harriet J.
Pure Fisetin