Metabolism
Pure Berberine, Manapura, .
Metabolism
Pure Berberine
Metabolism
Pure Berberine, Manapura, .

Pure Berberine
Cellular Health

£45.00

99.30% Pure BerberineNon-SyntheticProven BioavailabilityVegan & Gluten FreecGMP & ISO 9001 Certified Production

BENEFITS

Berberine works by activating AMPK, known as the body’s metabolic master switch.

Berberine has been clinically studied and shown to support weight management, blood glucose and mitochondrial function.

WHY MANAPURA

Manapura's Pure Berberine is sourced from the Berberis Aristata plant, natural + highly bioavailable making it a superior choice for supplementation.

Every batch undergoes rigorous heavy metal and toxin screening, and is third-party tested in ILAC-MRA accredited labs.  All products are manufactured in ISO 9001 and cGMP-certified facilities.

One-time

£45.00

Daily supplementation over 12 weeks has been shown to have significant effects on blood glucose levels, as well as improved lipid biomarkers.

Potential benefits of taking Berberine include:

  • Blood Sugar Support: Berberine has been shown to improve insulin sensitivity and help regulate blood sugar levels.
  • Cholesterol Management: Helps lower LDL ("bad" cholesterol) and triglycerides while increasing HDL ("good" cholesterol), supporting cardiovascular health.
  • Weight Control: May enhance metabolism, reduce fat storage, and support healthy weight management.
  • Gut Health Optimisation: Exhibits antimicrobial properties that help balance gut microbiota, promoting digestive health and overall well-being.
  • Anti-Inflammatory and Antioxidant Properties: Protects cells from oxidative damage and helps reduce chronic inflammation.

For maximum effectiveness, take one capsule up to three times per day with a meal for optimal absorption.

Berberine can be taken at any time of day; however, taking it at the same time every day is recommended.

Contains 60 capsules. One capsule contains 500mg of pure Berberine, naturally sourced from Berberis Aristata plant extract.

The capsule shell is made from 100% vegetable cellulose.

  • Vegan and Vegetarian
  • Gluten Free
  • Non-GMO
  • Allergen Free
  • Halal / Kosher Friendly

This product is intended for use by healthy adults only. Do not take if you are pregnant or breastfeeding.

For best results, complement your supplement routine with a balanced diet. Always consult with your doctor or healthcare professional before beginning any supplement, and never exceed the recommended daily dose.

UK ORDERS:

  • Standard Delivery (FREE):Delivered via Royal Mail 48H service.
  • Express Delivery (£3.95): Delivered via Royal Mail 24H service..

INTERNATIONAL ORDERS:

  • Standard Delivery (FREE): Delivered via Fedex Economy Services, 3-7 days.
  • Express Delivery (£3.95): Delivered via Fedex Prioirty Services, 2-4 days.

We are proud to cover customs, duties and taxes for our international customers.
Pure Berberine
£45.00
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Clinically studied for potency & absorption, we extract our Berberine naturally from the Berberis Aristata Plant, providing 99.3% purity.

Every batch undergoes rigorous heavy metal and toxin screening, and is third-party tested in ILAC-MRA accredited labs.  All products are manufactured in ISO 9001 and cGMP-certified facilities. We are proud to set the standard for traceability and rigorous safety.

Pure Berberine Supplement FAQs

What is Berberine, and how does it benefit metabolism?

Berberine is a natural compound that can support blood sugar, weight management, and cardiovascular wellness.

 How long do I need to supplement for to achieve the benefits?

Daily supplementation over 12 weeks has been shown to have significant effects on blood glucose levels, as well as improved lipid biomarkers.

 Can I take Berberine with other blood sugar and blood pressure medications?

Berberine may interact with medications for blood sugar, and blood pressure. Always consult your healthcare provider before combining it with prescriptions.

 What’s the optimal daily dosage of Berberine?

The most studied dosage is 500 mg, 2–3 times per day (totaling 1000–1500 mg/day), split between meals for best results.

 How should I take Berberine?

Take 1 capsule up to 3 times daily with meals for the best absorption and effectiveness.
What is Berberine, and how does it benefit metabolism?
How long do I need to supplement for to achieve the benefits?
Can Berberine help with weight loss?
Can I take Berberine with other blood sugar and blood pressure medications?
What’s the optimal daily dosage of Berberine?
How should I take Berberine?

We use pharmaceutical-grade glass vessels to protect against UV degradation and endocrine disruption.

Preserving potency and stability, our non-leaching amber glass provides eco-friendly, reusable, and toxin-free storage that meets the highest standards of laboratory integrity.

Berberine is a powerful bioactive compound found in plants like barberry, goldenseal, and tree turmeric. Used for centuries in traditional Chinese and Ayurvedic medicine, it is known for its ability to regulate metabolism and support overall health.

At a molecular level, berberine supports the activation of AMP-activated protein kinase (AMPK), often referred to as the "metabolic master switch." This important enzyme plays a role in maintaining energy balance and supporting healthy glucose metabolism. Early studies suggest that berberine may help promote overall metabolic health and support insulin function as part of a balanced lifestyle.

Additionally, Berberine can support cardiovascular health by maintaining healthy cholesterol and triglyceride levels, reducing inflammation, and improving circulation. Taking Berberine has also been linked to improved gut health by modulating the microbiome. With its wide-ranging properties, it is considered one of the most versatile natural supplements for metabolic and cardiovascular wellness.

LEARN

All of our products are supported by clinical studies.

Berberine: A Clinically Validated Insulin Sensitiser for PCOS

READ THE STUDY NOTES HERE

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Meet our Advisors

Dr. Cherry Lo, Ph.D., is a researcher specialising in pathology and immunity, with degrees from CUHK and the University of Hong Kong. Her work focuses on the interaction between NK cells and rheumatoid arthritis, providing new insights into disease mechanisms. As a research scientist, she contributes to advancements in longevity science. With a passion for immunology and translational research, Dr. Lo is dedicated to uncovering innovative solutions for age-related diseases and immune health.

DR. CHERRY LO, Ph.D

Longevity Expert

READ INTERVIEW

Dr. Cherry Lo, Ph.D., is a researcher specialising in pathology and immunity, with degrees from CUHK and the University of Hong Kong. Her work focuses on the interaction between NK cells and rheumatoid arthritis, providing new insights into disease mechanisms. As a research scientist, she contributes to advancements in longevity science. With a passion for immunology and translational research, Dr. Lo is dedicated to uncovering innovative solutions for age-related diseases and immune health.

DR. CHERRY LO, Ph.D

Longevity Expert

Ben is the founder and head grower at one of the UK’s leading fungi farms, where he cultivates a deep passion for mushroom cultivation and education. Since launching his farm in 2022, he has dedicated himself to exploring fungi’s medicinal and ecological potential. Ben is a regular speaker at functional mushroom conferences around the UK where he shares his knowledge and enthusiasm for the fungal kingdom. He aims to inspire others to connect with these fascinating organisms.

BEN GIBSON

Mycology Expert

Ben is the founder and head grower at one of the UK’s leading fungi farms, where he cultivates a deep passion for mushroom cultivation and education. Since launching his farm in 2022, he has dedicated himself to exploring fungi’s medicinal and ecological potential. Ben is a regular speaker at functional mushroom conferences around the UK where he shares his knowledge and enthusiasm for the fungal kingdom. He aims to inspire others to connect with these fascinating organisms.

BEN GIBSON

Mycology Expert

Carolina is a holistic sleep coach specialising in circadian biology, nutritional therapy, and biohacking. With over seven years of experience, she blends scientific research with ancestral wisdom to help clients achieve deep, restorative sleep naturally. Her expertise in light exposure, stress resilience, and nervous system regulation allows her to create personalised, sustainable solutions without reliance on medication. Carolina is passionate about empowering individuals to optimise their sleep and overall well-being through evidence-based, holistic practices.

CAROLINA RAMUSKI

Sleep Expert

Carolina is a holistic sleep coach specialising in circadian biology, nutritional therapy, and biohacking. With over seven years of experience, she blends scientific research with ancestral wisdom to help clients achieve deep, restorative sleep naturally. Her expertise in light exposure, stress resilience, and nervous system regulation allows her to create personalised, sustainable solutions without reliance on medication. Carolina is passionate about empowering individuals to optimise their sleep and overall well-being through evidence-based, holistic practices.

CAROLINA RAMUSKI

Sleep Expert

Customer Reviews

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Louise B.
Pure Berberine

Super quick delivery, and its a nice touch that this sits pretty in my bathroom!

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\Kieran B.
Pure Berberine

Fast delivery, thank you. Will repurchase once I get through it all - rather shop from a UK brand

B
Ben M.
Pure Berberine

Glad it's a UK brand - would recommend

K
Kimberley S.
Pure Berberine

I'm 29 and was recently advised to look into Metformin for my PCOS, I did a lot of research and came across several studies comparing Berberine to Metformin, and so gave Berberine a try. I chose Manapura because purity and third-party testing are non-negotiables for me, especially with supplements. After a couple of months, I've noticed much higher energy throughout the day and less of that post-carb crash that my fellow PCOS girlies will know well!! I also appreciate that it feels like a more natural alternative without having to rely on medication at my age.

D
Dominic P.
Pure Berberine

I'm 30 and started taking berberine after hearing it could support blood sugar balance and make it easier to maintain a healthy weight. I've always struggled with sugar cravings and energy dips in the afternoon, but within a couple of weeks I noticed they were much less intense.

I like that berberine is a natural supplement with a lot of research behind it. The capsules are easy to take and I haven't had any side effects.

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