DNA Support
Pure TMG, Manapura, .
DNA Support
Pure TMG, Manapura, .
DNA Support
Pure TMG, Manapura, .

Pure TMG

Cellular Health

£35.00

99.62% Pure TMGNon-SyntheticProven BioavailabilityVegan & Gluten FreecGMP & ISO 9001 Certified Production

BENEFITS

TMG is a common component of protocols aimed at supporting liver function, energy production, and homocysteine balance, supporting heart and cognitive health. It is especially valued for its synergistic effect with NMN, helping to support the body's natural NAD+ metabolism and energy systems.

WHY MANAPURA

Manapura’s TMG is purposefully dosed at 500mg, a high strength and potent product to align with leading methylation research.

Every batch undergoes rigorous heavy metal and toxin screening, and is third-party tested in ILAC-MRA accredited labs.  All products are manufactured in ISO 9001 and cGMP-certified facilities.

One-time

£35.00

Of the observable effects, robust human results confirm that 6 weeks is an evidence-backed duration for TMG’s noticeable effects in active, resistance-training individuals.

Potential benefits of TMG include:

  • Improved Body Composition: TMG supplementation has been shown to reduce fat mass and body fat percentage, and increase lean muscle mass
  • Heart Health: TMG may help lower homocysteine levels, which could improve heart health. However, further research and studies are needed here.
  • Possible Athletic Performance Enhancement: Some studies suggest TMG may reduce fatigue during exercise, boost protein production, and increase creatine synthesis providing energy to muscle cells.
  • Insulin Regulation: TMG supplementation may help prevent insulin resistance and improve insulin sensitivity. Studies in animals have shown promising results, but more research is needed in humans.
  • Anti-Inflammatory: Evidence suggests that TMG may have anti-inflammatory and antioxidative properties.
  • Sleep Aid: TMG can aid sleep due to the Glycine content.

For maximum effectiveness, take two capsules daily with water.

Although TMG is effective any time of day, some studies suggest it may support sleep, making it an ideal choice for evening use.

Contains 60 capsules. One capsule contains 500mg of Pure TMG.

The capsule shell is made from 100% vegetable cellulose.

  • Vegan and Vegetarian
  • Gluten Free
  • Non-GMO
  • Allergen Free
  • Halal / Kosher Friendly

This product is intended for use by healthy adults only. Do not take if you are pregnant or breastfeeding. TMG is not suitable for individuals with a history of kidney disease.

For best results, complement your supplement routine with a balanced diet. Always consult with your doctor or healthcare professional before beginning any supplement, and never exceed the recommended daily dose.

UK ORDERS:

  • Standard Delivery (FREE):Delivered via Royal Mail 48H service.
  • Express Delivery (£3.95): Delivered via Royal Mail 24H service..

INTERNATIONAL ORDERS:

  • Standard Delivery (FREE): Delivered via Fedex Economy Services, 3-7 days.
  • Express Delivery (£3.95): Delivered via Fedex Prioirty Services, 2-4 days.

We are proud to cover customs, duties and taxes for our international customers.
Pure TMG
£35.00
Partner logo
Partner logo
Partner logo
Partner logo
Partner logo
Partner logo
Partner logo
Partner logo
Partner logo
Partner logo
Partner logo
Partner logo

Purposefully dosed at 500mg to align with leading methylation research, our TMG is certified at 99.62% purity.

Every batch undergoes rigorous heavy metal and toxin screening, and is third-party tested in ILAC-MRA accredited labs.  All products are manufactured in ISO 9001 and cGMP-certified facilities. We are proud to set the standard for traceability and rigorous safety.

Pure TMG Supplement FAQs

What are the benefits of TMG?

TMG has been shown to potentially support cardiovascular health, liver maintenance, and DNA methylation, key for cellular function.

 How long do I need to supplement for to achieve the benefits?

Of the observable effects, robust human results confirm that 6 weeks is an evidence-backed duration for TMG’s noticeable effects in active, resistance-training individuals.

 Why is TMG often paired with NMN?

TMG acts as a methyl donor; a substance that donates a methyl (-CH3) group to other molecules. NMN increases NAD+ levels, and this process can be further optimised by increasing the levels of methyl donors in our body.

 Can TMG enhance physical performance?

Yes, studies have shown that TMG may support endurance and muscle recovery. For this reason it pairs well with not only NMN, but also Cordyceps.

 Is TMG safe?

TMG has been studied for cardiovascular health and is considered safe for healthy humans when used within recommended doses. Always consult your health practitioner if you are unsure about introducing new supplements to your routine.
What are the benefits of TMG?
How long do I need to supplement for to achieve the benefits?
When should I take TMG?
Why is TMG often paired with NMN?
Can TMG enhance physical performance?
Is TMG safe?

We use pharmaceutical-grade glass vessels to protect against UV degradation and endocrine disruption.

Preserving potency and stability, our non-leaching amber glass provides eco-friendly, reusable, and toxin-free storage that meets the highest standards of laboratory integrity.

Our high-strength TMG capsules deliver a pure, bioavailable dose of this important nutrient, designed to support key cellular and metabolic functions.

TMG, also known as Betaine Anhydrous, is a naturally occurring compound found in foods like spinach, beets, shellfish, and whole grains.

TMG plays a key role in methylation — a core biochemical process involved in gene expression, DNA stability, and overall cellular health. As one of the body’s primary methyl donors, TMG contributes to overall cellular harmony and optimal function.

This supplement is a common component in wellness protocols aimed at supporting liver function, cellular energy production, and homocysteine balance. It is especially valued for its synergistic use with NMN, helping to support the body's natural NAD+ metabolism and energy systems.

LEARN

All of our products are supported by clinical studies.

TMG, Milk Thistle, or NAC? Comparing the Best Supplements for Liver Support

READ THE STUDY NOTES HERE

Ultimate NAD+ Trio

An advanced, clinically-minded stack for those building a disciplined longevity protocol. Suited for those requiring a daily routine formulated to help maintain normal cellular energy processes as we age. Containing NMN, TMG and Trans-Resveratrol, save 15% on the ultimate longevity protocol.

Shop now

NAD+ Duo

Suited for those requiring steady daytime energy, clear-thinking and task focus without the use of stimulants. NMN supports NAD+ levels for brain energy and cognition, while TMG enhances methylation, liver and heart health. Shop the purest NAD+ supplement stack and save 15% when purchasing together.

Shop now

Meet our Advisors

Dr. Cherry Lo, Ph.D., is a researcher specialising in pathology and immunity, with degrees from CUHK and the University of Hong Kong. Her work focuses on the interaction between NK cells and rheumatoid arthritis, providing new insights into disease mechanisms. As a research scientist, she contributes to advancements in longevity science. With a passion for immunology and translational research, Dr. Lo is dedicated to uncovering innovative solutions for age-related diseases and immune health.

DR. CHERRY LO, Ph.D

Longevity Expert

READ INTERVIEW

Dr. Cherry Lo, Ph.D., is a researcher specialising in pathology and immunity, with degrees from CUHK and the University of Hong Kong. Her work focuses on the interaction between NK cells and rheumatoid arthritis, providing new insights into disease mechanisms. As a research scientist, she contributes to advancements in longevity science. With a passion for immunology and translational research, Dr. Lo is dedicated to uncovering innovative solutions for age-related diseases and immune health.

DR. CHERRY LO, Ph.D

Longevity Expert

Ben is the founder and head grower at one of the UK’s leading fungi farms, where he cultivates a deep passion for mushroom cultivation and education. Since launching his farm in 2022, he has dedicated himself to exploring fungi’s medicinal and ecological potential. Ben is a regular speaker at functional mushroom conferences around the UK where he shares his knowledge and enthusiasm for the fungal kingdom. He aims to inspire others to connect with these fascinating organisms.

BEN GIBSON

Mycology Expert

Ben is the founder and head grower at one of the UK’s leading fungi farms, where he cultivates a deep passion for mushroom cultivation and education. Since launching his farm in 2022, he has dedicated himself to exploring fungi’s medicinal and ecological potential. Ben is a regular speaker at functional mushroom conferences around the UK where he shares his knowledge and enthusiasm for the fungal kingdom. He aims to inspire others to connect with these fascinating organisms.

BEN GIBSON

Mycology Expert

Carolina is a holistic sleep coach specialising in circadian biology, nutritional therapy, and biohacking. With over seven years of experience, she blends scientific research with ancestral wisdom to help clients achieve deep, restorative sleep naturally. Her expertise in light exposure, stress resilience, and nervous system regulation allows her to create personalised, sustainable solutions without reliance on medication. Carolina is passionate about empowering individuals to optimise their sleep and overall well-being through evidence-based, holistic practices.

CAROLINA RAMUSKI

Sleep Expert

Carolina is a holistic sleep coach specialising in circadian biology, nutritional therapy, and biohacking. With over seven years of experience, she blends scientific research with ancestral wisdom to help clients achieve deep, restorative sleep naturally. Her expertise in light exposure, stress resilience, and nervous system regulation allows her to create personalised, sustainable solutions without reliance on medication. Carolina is passionate about empowering individuals to optimise their sleep and overall well-being through evidence-based, holistic practices.

CAROLINA RAMUSKI

Sleep Expert

Customer Reviews

Based on 12 reviews
100%
(12)
0%
(0)
0%
(0)
0%
(0)
0%
(0)
L
Louise B.
Pure TMG

Quick delivery thank you! Trying these out as a liver supplement.

C
Camilla B.
Pure TMG

I bought this as was looking into liver support after noticing sluggish digestion and fatigue and couldn't pin point it. I came across a few studies showing TMG's role in improving liver function and methylation, so I gave TMG a try. I've taken for 3 weeks and so far do feel way less bloated, and more balanced. It's reassuring to know this is a UK company too.

A
Andy M.
Pure TMG

I ordered the NAD Duo as my PT recommended the Manapura NMN - noticed a much better recovery after training since taking both for the last 3 weeks. It all feels very premium, will be trying more of the range.

D
Dominic P.
Pure TMG

I've been taking NMN for a year and love it. I saw Dr. Huberman say to add TMG, so I gave it a try.

Now my energy feels steadier and my focus better. It's easy to take, supports heart and liver health, and I like that it comes in glass instead of plastic.

A
Andrew H.
Pure TMG

I take TMG with NMM to increase NAD+ and these products are high purity. Overall feeling much better. Also an improvement in sleep quality.

123