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NMN is the most efficient NAD+ booster, supporting cellular repair & anti-ageing.
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Clinically researched to support Heart Health, Metabolism & Liver function.
Pure TMG
Cellular Health
Manapura Pure TMG supplement gives you pure trimethylglycine, a nutrient found in foods like spinach that helps support liver detox, heart health and metabolism.
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Of the observable effects, robust human results confirm that 6 weeks is an evidence-backed duration for TMG’s noticeable effects in active, resistance-training individuals.
For maximum effectiveness, take two capsules daily with water.
Although TMG is effective any time of day, some studies suggest it may support sleep, making it an ideal choice for evening use.
Contains 60 capsules. One capsule contains 500mg of Pure TMG.
The capsule shell is made from 100% vegetable cellulose.
This product is intended for use by healthy adults only. Do not take if you are pregnant or breastfeeding. TMG is not suitable for individuals with a history of kidney disease.
For best results, complement your supplement routine with a balanced diet. Always consult with your doctor or healthcare professional before beginning any supplement, and never exceed the recommended daily dose.
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For maximum effectiveness, take two capsules daily with water.
Although TMG is effective any time of day, some studies suggest it may support sleep, making it an ideal choice for evening use.
Dosage

Store in a cool, dry place. Keep away from extreme heat and direct sunlight. Reseal container after each use. Keep out of reach of children.
Storage

This product is intended for use by healthy adults only. Do not take if you are pregnant or breastfeeding. TMG is not suitable for individuals with a history of kidney disease.
For best results, complement your supplement routine with a balanced diet. Always consult with your doctor or healthcare professional before beginning any supplement, and never exceed the recommended daily dose.
Precautions
Batch tested for heavy metals, toxins, and unwanted contaminants. Nothing gets shipped unless it meets the highest safety standards.
TMG has been shown to potentially support cardiovascular health, liver maintenance, and DNA methylation, key for cellular function.
How long do I need to supplement for to achieve the benefits?Of the observable effects, robust human results confirm that 6 weeks is an evidence-backed duration for TMG’s noticeable effects in active, resistance-training individuals.
Why is TMG often paired with NMN?TMG acts as a methyl donor; a substance that donates a methyl (-CH3) group to other molecules. NMN increases NAD+ levels, and this process can be further optimised by increasing the levels of methyl donors in our body.
Can TMG enhance physical performance?Yes, studies have shown that TMG may support endurance and muscle recovery. For this reason it pairs well with not only NMN, but also Cordyceps.
Is TMG safe?TMG has been studied for cardiovascular health and is considered safe for healthy humans when used within recommended doses. Always consult your health practitioner if you are unsure about introducing new supplements to your routine.
NMN is the most efficient NAD+ booster, supporting cellular repair & anti-ageing.
Order yours now for 50% off.

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Quick delivery thank you! Trying these out as a liver supplement.
I bought this as was looking into liver support after noticing sluggish digestion and fatigue and couldn't pin point it. I came across a few studies showing TMG's role in improving liver function and methylation, so I gave TMG a try. I've taken for 3 weeks and so far do feel way less bloated, and more balanced. It's reassuring to know this is a UK company too.
I ordered the NAD Duo as my PT recommended the Manapura NMN - noticed a much better recovery after training since taking both for the last 3 weeks. It all feels very premium, will be trying more of the range.
I've been taking NMN for a year and love it. I saw Dr. Huberman say to add TMG, so I gave it a try.
Now my energy feels steadier and my focus better. It's easy to take, supports heart and liver health, and I like that it comes in glass instead of plastic.
Added TMG to my stack alongside NMN to boost NAD+ levels and it's made a big difference. Energy feels more balanced, and generally feel a lot better.
Dr. Cherry Lo, Ph.D., is a researcher specialising in pathology and immunity, with degrees from CUHK and the University of Hong Kong. Her work focuses on the interaction between NK cells and rheumatoid arthritis, providing new insights into disease mechanisms. As a research scientist, she contributes to advancements in longevity science. With a passion for immunology and translational research, Dr. Lo is dedicated to uncovering innovative solutions for age-related diseases and immune health.
Dr. Cherry Lo, Ph.D., is a researcher specialising in pathology and immunity, with degrees from CUHK and the University of Hong Kong. Her work focuses on the interaction between NK cells and rheumatoid arthritis, providing new insights into disease mechanisms. As a research scientist, she contributes to advancements in longevity science. With a passion for immunology and translational research, Dr. Lo is dedicated to uncovering innovative solutions for age-related diseases and immune health.
DR. CHERRY LO, Ph.D
Longevity Expert
Ben is the founder and head grower at one of the UK’s leading fungi farms, where he cultivates a deep passion for mushroom cultivation and education. Since launching his farm in 2022, he has dedicated himself to exploring fungi’s medicinal and ecological potential. Ben is a regular speaker at functional mushroom conferences around the UK where he shares his knowledge and enthusiasm for the fungal kingdom. He aims to inspire others to connect with these fascinating organisms.
BEN GIBSON
Mycology Expert
Ben is the founder and head grower at one of the UK’s leading fungi farms, where he cultivates a deep passion for mushroom cultivation and education. Since launching his farm in 2022, he has dedicated himself to exploring fungi’s medicinal and ecological potential. Ben is a regular speaker at functional mushroom conferences around the UK where he shares his knowledge and enthusiasm for the fungal kingdom. He aims to inspire others to connect with these fascinating organisms.
BEN GIBSON
Mycology Expert
Carolina is a holistic sleep coach specialising in circadian biology, nutritional therapy, and biohacking. With over seven years of experience, she blends scientific research with ancestral wisdom to help clients achieve deep, restorative sleep naturally. Her expertise in light exposure, stress resilience, and nervous system regulation allows her to create personalised, sustainable solutions without reliance on medication. Carolina is passionate about empowering individuals to optimise their sleep and overall well-being through evidence-based, holistic practices.
CAROLINA RAMUSKI
Sleep Expert
Carolina is a holistic sleep coach specialising in circadian biology, nutritional therapy, and biohacking. With over seven years of experience, she blends scientific research with ancestral wisdom to help clients achieve deep, restorative sleep naturally. Her expertise in light exposure, stress resilience, and nervous system regulation allows her to create personalised, sustainable solutions without reliance on medication. Carolina is passionate about empowering individuals to optimise their sleep and overall well-being through evidence-based, holistic practices.
CAROLINA RAMUSKI
Sleep Expert
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