ADVANCED NAD+
ADVANCED NAD+
NMN ∘ TMG ∘ Trans-Resveratrol
NMN fuels your cells. TMG puts that energy to work. Trans-Resveratrol helps it last.
Accreditations
✓ Boosts NAD+ levels & energy production
✓ Supports overall cellular health
✓ Supports a healthy metabolism
✓ Supports anti-ageing
Supports deep, restorative sleep
Customers report increases in energy and other observable signs of healthy aging within 4-6 weeks, with NAD⁺ levels clinically shown to significantly increase within this period.
Pure NMN:
One capsule contains 500mg of 99% pure NMN*.
The capsule shell is made from 100% vegetable cellulose.
- Vegan and Vegetarian
- Gluten Free
- Non-GMO
- Allergen Free
- Halal / Kosher Friendly
Pure Trans-Resveratrol:
One capsule contains 500mg of Pure Trans-Resveratrol*, naturally sourced from Japonica plant extract. Research suggests that Trans-Resveratrol*, sourced from Japonica is highly bioavailable and effective, making it a superior choice for supplementation.
The capsule shell is made from 100% vegetable cellulose.
- Vegan and Vegetarian
- Gluten Free
- Non-GMO
- Allergen Free
- Halal / Kosher Friendly
Pure TMG:
One capsule contains 500mg of Pure TMG*.
The capsule shell is made from 100% vegetable cellulose.
- Vegan and Vegetarian
- Gluten Free
- Non-GMO
- Allergen Free
- Halal / Kosher Friendly
Pure NMN:
For maximum effectiveness, take two capsules daily with water.
Pure NMN can be taken at any time of day; however, taking it at the same time every day is recommended.
Pure TMG:
For maximum effectiveness, take two capsules daily with water.
Although TMG is effective any time of day, some studies suggest it may support sleep, making it an ideal choice for evening use.
Pure Trans-Reservatrol:
For maximum effectiveness, take two capsules daily with a meal for optimal absorption. For best results, complement your routine with a balanced diet rich in healthy fats.
Pure Trans-Reservatrol can be taken at any time of day; however, taking it at the same time every day is recommended.
This product is intended for use by healthy adults only. Do not take if you are pregnant or breastfeeding.
For best results, complement your supplement routine with a balanced diet. Always consult with your doctor or healthcare professional before beginning any supplement, and never exceed the recommended daily dose.
Specifically regarding Pure TMG:
TMG is not suitable for individuals with a history of kidney disease.
Specifically regarding Pure Trans-Reservatrol:
Do not take if you are pregnant, breastfeeding, or using anticoagulant or antiplatelet medications—for example, warfarin (Coumadin), heparin, aspirin, or clopidogrel (Plavix)—which are typically prescribed to individuals with cardiovascular or clotting concerns.
UK ORDERS:
- Standard Delivery (FREE):Delivered via Royal Mail 48H service.
- Express Delivery (£3.95): Delivered via Royal Mail 24H service..
INTERNATIONAL ORDERS:
- Standard Delivery (FREE): Delivered via Fedex Economy Services, 3-7 days.
- Express Delivery (£3.95): Delivered via Fedex Prioirty Services, 2-4 days.
We are proud to cover customs, duties and taxes for our international customers.
NAD+ Activation: Energy, Sleep, Cellular Repair & Anti-Ageing
Our most advanced NAD+ stack: NMN, TMG & Trans-Resveratrol.
Ultra Pure
Medical Grade
Micronised For Maximum Absorption
Vegan & Gluten-Free
Manapura® VS Most Brands On The Market
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Perfectly combined longevity routines built to enhance your goals.
Guidance
Pure NMN:
For maximum effectiveness, take two capsules daily with water.
Pure NMN can be taken at any time of day; however, taking it at the same time every day is recommended.
Pure TMG:
For maximum effectiveness, take two capsules daily with water.
Although TMG is effective any time of day, some studies suggest it may support sleep, making it an ideal choice for evening use.
Pure Trans-Reservatrol:
For maximum effectiveness, take two capsules daily with a meal for optimal absorption. For best results, complement your routine with a balanced diet rich in healthy fats.
Pure Trans-Reservatrol can be taken at any time of day; however, taking it at the same time every day is recommended.
Dosage
Store in a cool, dry place. Keep away from extreme heat and direct sunlight. Reseal container after each use. Keep out of reach of children.
Storage
This product is intended for use by healthy adults only. Do not take if you are pregnant or breastfeeding.
For best results, complement your supplement routine with a balanced diet. Always consult with your doctor or healthcare professional before beginning any supplement, and never exceed the recommended daily dose.
Specifically regarding Pure TMG:
TMG is not suitable for individuals with a history of kidney disease.
Specifically regarding Pure Trans-Reservatrol:
Do not take if you are pregnant, breastfeeding, or using anticoagulant or antiplatelet medications—for example, warfarin (Coumadin), heparin, aspirin, or clopidogrel (Plavix)—which are typically prescribed to individuals with cardiovascular or clotting concerns.
Precautions
Advanced NAD+ Supplement FAQs
NMN is naturally present in our bodies, and studies indicate NMN supplementation is well-tolerated, with clinical trials showing no significant adverse effects.
How long do I need to supplement for to achieve the benefits?Customers report increases in energy and other observable signs of healthy aging within 4-6 weeks, with NAD⁺ levels clinically shown to significantly increase within this period.
Why is TMG often paired with NMN?TMG acts as a methyl donor; a substance that donates a methyl (-CH3) group to other molecules. NMN increases NAD+ levels, and this process can be further optimized by increasing the levels of methyl donors in our body.
Can TMG enhance physical performance?Yes, studies show TMG improves endurance, muscle recovery, and overall strength. For this reason it pairs well with not only NMN, but also Cordyceps.
How is Manapura NMN different from other NMN available?Manapura NMN is produced using naturally occurring enzymes, within a state-of-the-art facility. This enzymatic production method leads solely to the production of the beta-NMN isomer. This is the only NMN variant used in the human body, and means Manapura NMN is the highest bioavailable NMN on the market today.
Every single batch is tested by third-party labs.
Batch tested for heavy metals, toxins, and unwanted contaminants. Nothing gets shipped unless it meets the highest safety standards.
Latest Longevity News and Studies
NMN increases NAD⁺ availability, which in turn enables Resveratrol to activate sirtuins more effectively. When combined, these compounds address both the fuel (NAD⁺) and the activation pathways (sirtuins) of cellular repair and regeneration.
Why you should pair NMN and Trans-Resveratrol for maximum longevity benefit
The Bryan Johnson Blueprint is built around measurable biological age reduction. So when Hyaluronic Acid appears on the supplement list, it’s worth asking why.
Why Bryan Johnson Added Hyaluronic Acid to His Blueprint Stack
Hair health is one of the clearest signs of ageing. Over time, hair can become thinner, more brittle, or start turning grey. While most products target the surface, true hair vitality begins deeper - inside your cells. That’s where Nicotinamide Mononucleotide (NMN) comes in.
Can NMN help reverse grey hair and hair loss?
- 5 stars: 50 (96%)
- 4 stars: 1 (2%)
- 3 stars: 1 (2%)
- 2 stars: 0 (0%)
- 1 star: 0 (0%)
Been taking NMN for 3 months and noticed a positive swing in energy levels. Less inflammation as well. Decent product
Absolutely in love with the product and the Brand it self starting packaging and the quantity of products ingredients it’s amazing 🤩
The product itself is great. Already feeling multiple benefits and enjoying taking them. Easy to take. Recommended.
Still too early to tell………….
Love the product NMN
Very impressed with the consistency and professionalism. Delivery was prompt, everything arrived in great condition and the purity of the NMN has encouraged me to become a repeat customer
Love this brand! With all the noise online re supplements I really didn’t know where to start, but a friend recommended Manapura and I’m really happy I gave it a try! My sleep and energy levels have significantly improved and I just feel generally better
Very good. Speedy delivery
Purchased NMN, TMG & Resveratrol as an NAD+ Stack. Impressed with the results. Feel less achey and certainly more energy
Got the NAD+ stack. Feeling good so far. Can tell its a premium product quite expensive but think I will be worth the extra pennies
Taking the longevity essentials stack and noticeable increase in energy.
Taking NMN for about 3 weeks now and def sleeping better. Also seems to have calmed inflammation. Nice product
Beautiful packaging! Just started NMN so will see how it goes
Biggest difference is energy levels and sleep quality. Noticeable difference
Your products are excellent well done ,hope you do very well
Was a bit cynical about NMN initially as don't really take supplements, but after a few months I feel better in myself.
I really feel better, so l am very happy about it🙏
Great product! It's made a significant impact on my energy levels. Great service too. Highly recommend!
My skin feels firmer, I have not yet found improvement on my eyebrows where growth is still weak since a chemptheraphy more than 2years ago.
Have definitely felt the benefits since taking this product.
very happy will buy again
Have bought NMN from 4 different companies over the years, but you can tell as soon as the box arrives that this is next level
Ive been thinking about taking NMN for a while now and feeling very good after 6 weeks. Lots more energy. Lovely packaging as well
Taken a few NMN products but this one is powerful. Improved sleep and generally more energy day to day
Great customer service, very helpful. My order came quick
Came v quick, topping up for my boyfriend
Meet our Advisors
Dr. Cherry Lo, Ph.D., is a researcher specialising in pathology and immunity, with degrees from CUHK and the University of Hong Kong. Her work focuses on the interaction between NK cells and rheumatoid arthritis, providing new insights into disease mechanisms. As a research scientist, she contributes to advancements in longevity science. With a passion for immunology and translational research, Dr. Lo is dedicated to uncovering innovative solutions for age-related diseases and immune health.
Dr. Cherry Lo, Ph.D., is a researcher specialising in pathology and immunity, with degrees from CUHK and the University of Hong Kong. Her work focuses on the interaction between NK cells and rheumatoid arthritis, providing new insights into disease mechanisms. As a research scientist, she contributes to advancements in longevity science. With a passion for immunology and translational research, Dr. Lo is dedicated to uncovering innovative solutions for age-related diseases and immune health.
DR. CHERRY LO, Ph.D
Longevity Expert
Ben is the founder and head grower at one of the UK’s leading fungi farms, where he cultivates a deep passion for mushroom cultivation and education. Since launching his farm in 2022, he has dedicated himself to exploring fungi’s medicinal and ecological potential. Ben is a regular speaker at functional mushroom conferences around the UK where he shares his knowledge and enthusiasm for the fungal kingdom. He aims to inspire others to connect with these fascinating organisms.
BEN GIBSON
Mycology Expert
Ben is the founder and head grower at one of the UK’s leading fungi farms, where he cultivates a deep passion for mushroom cultivation and education. Since launching his farm in 2022, he has dedicated himself to exploring fungi’s medicinal and ecological potential. Ben is a regular speaker at functional mushroom conferences around the UK where he shares his knowledge and enthusiasm for the fungal kingdom. He aims to inspire others to connect with these fascinating organisms.
BEN GIBSON
Mycology Expert
Carolina is a holistic sleep coach specialising in circadian biology, nutritional therapy, and biohacking. With over seven years of experience, she blends scientific research with ancestral wisdom to help clients achieve deep, restorative sleep naturally. Her expertise in light exposure, stress resilience, and nervous system regulation allows her to create personalised, sustainable solutions without reliance on medication. Carolina is passionate about empowering individuals to optimise their sleep and overall well-being through evidence-based, holistic practices.
CAROLINA RAMUSKI
Sleep Expert
Carolina is a holistic sleep coach specialising in circadian biology, nutritional therapy, and biohacking. With over seven years of experience, she blends scientific research with ancestral wisdom to help clients achieve deep, restorative sleep naturally. Her expertise in light exposure, stress resilience, and nervous system regulation allows her to create personalised, sustainable solutions without reliance on medication. Carolina is passionate about empowering individuals to optimise their sleep and overall well-being through evidence-based, holistic practices.
CAROLINA RAMUSKI
Sleep Expert