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Cellular Renewal Trio, Manapura, .
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Pure Berberine, Manapura, .
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Natural Spermidine, Manapura, .
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Pure Fisetin, Manapura, .

Cellular Renewal Trio

Cellular Health

Save 9%

£150.00 £136.00

Ultra Potent, Clinical Strength DosesNon-SyntheticProven BioavailabilityVegan & Gluten FreecGMP & ISO 9001 Certified Production

BENEFITS

Three targeted actives. One disciplined daily routine for cellular upkeep, steadier energy around meals, and a clear, composed baseline. Suited for those looking for even daytime energy with a reduced afternoon dip, clearer cognition and more consistent training output.

SPERMIDINE: Researched for roles in cellular housekeeping (autophagy) pathways.

BERBERINE: A staple in metabolic research, linked with pathways that help your body use fuel efficiently.

FISETIN: A flavonoid investigated for healthy-ageing biology, including cellular senescence research.

WHY MANAPURA

All Manapura products are meticulously sourced for optimal purity and bioavailability, providing you with ultra-potent compounds to deliver maximum, clinically-studied benefits.

Every batch of each product undergoes rigorous heavy metal and toxin screening, and is third-party tested in ILAC-MRA accredited labs. All products are manufactured in ISO 9001 and cGMP-certified facilities.

£136.00

Berberine:

One capsule contains 500mg of 98% Pure Berberine, naturally sourced from Berberis Aristata plant extract. Research suggests that Berberine sourced from Berberis Aristata is highly bioavailable and effective, making it a superior choice for supplementation.

The capsule shell is made from 100% vegetable cellulose.

  • Vegan and Vegetarian
  • Gluten Free
  • Non-GMO
  • Allergen Free
  • Halal / Kosher Friendly

Fisetin:

One capsule contains 400mg of pure Fisetin*.

The capsule shell is made from 100% vegetable cellulose.

  • Vegan and Vegetarian
  • Gluten Free
  • Non-GMO
  • Allergen Free
  • Halal / Kosher Friendly

Spermidine:

One capsule contains 350mg of natural Spermidine-rich wheat germ extract.

The capsule shell is made from 100% vegetable cellulose.

  • NOTE: CONTAINS GLUTEN
  • Vegan and Vegetarian
  • Non-GMO
  • Allergen Free
  • Halal / Kosher Friendly

Fisetin:

For maximum effectiveness, take one capsule daily with a meal for optimal absorption. For best results, complement your routine with a balanced diet rich in healthy fats.

Fisetin can be taken at any time of day; however, taking it at the same time every day is recommended.

Berberine:

For maximum effectiveness, take one capsule daily with a meal for optimal absorption.

Berberine can be taken at any time of day; however, taking it at the same time every day is recommended.

Spermidine:

For maximum effectiveness, take two capsules daily with a meal for optimal absorption. For best results, complement your routine with a balanced diet rich in healthy fats.

Spermidine can be taken at any time of day; however, taking it at the same time every day is recommended.

Fisetin:

For maximum effectiveness, take one capsule daily with a meal for optimal absorption. For best results, complement your routine with a balanced diet rich in healthy fats.

Fisetin can be taken at any time of day; however, taking it at the same time every day is recommended.

Berberine:

For maximum effectiveness, take one capsule daily with a meal for optimal absorption.

Berberine can be taken at any time of day; however, taking it at the same time every day is recommended.

Spermidine:

For maximum effectiveness, take two capsules daily with a meal for optimal absorption. For best results, complement your routine with a balanced diet rich in healthy fats.

Spermidine can be taken at any time of day; however, taking it at the same time every day is recommended.

This product is intended for use by healthy adults only. Do not take if you are pregnant or breastfeeding.

For best results, complement your supplement routine with a balanced diet. Always consult with your doctor or healthcare professional before beginning any supplement, and never exceed the recommended daily dose.

Specifically regarding Fisetin:

Do not take if you are pregnant, breastfeeding, or using anticoagulant or antiplatelet medications—for example, warfarin (Coumadin), heparin, aspirin, or clopidogrel (Plavix)—which are typically prescribed to individuals with cardiovascular or clotting concerns.

UK Orders 

  • Standard Delivery: Processed in 1–2 business days, delivered within 2 days.
  • Express Delivery: Processed in 1 business day, delivered next working day.
    During busy periods, processing may take slightly longer.

International Orders 

  • Processed within 2 business days.
  • Delivery takes 7–14 business days, depending on local customs.
    Customs duties vary by country and are the customer’s responsibility.

Carriers 

  • UK: Royal Mail Tracked48 (standard) or Royal Mail Express (next-day).
  • North America, EU, Asia Pacific: Shipped via Royal Mail, then passed to a local carrier. You’ll receive tracking once your order is dispatched.
Cellular Renewal Trio
£136.00 £150.00
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Clinically studied for potency & absorption, we extract our Berberine naturally from the Berberis Aristata Plant, providing 99.3% purity.

Every batch undergoes rigorous heavy metal and toxin screening in ILAC-MRA accredited labs and are manufactured in ISO 9001 and cGMP-certified facilities. We are proud to set the standard for traceability and rigorous safety.

Frequently Asked Questions

We use pharmaceutical-grade glass vessels to protect against UV degradation and endocrine disruption.

Preserving potency and stability, our non-leaching amber glass provides eco-friendly, reusable, and toxin-free storage that meets the highest standards of laboratory integrity.

LEARN

All of our products are supported by clinical studies.

Berberine & Fisetin: Two Emerging Solutions for PCOS Management

READ THE STUDY NOTES HERE

Customer Reviews

Based on 24 reviews
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Customer
Natural Spermidine

Interesting product, I'm new to this stuff but find the science behind this one quite interesting, don't think anything else I take does the same thing so will keep trying it.

L
Louise B.
Pure Berberine

Super quick delivery, and its a nice touch that this sits pretty in my bathroom!

\
\Louise B.
Pure Fisetin

Bought this as part of the trio, I'll admit I read about the use cases of Fisetin after ordering but now very excited to try, if my body needs anything right now it's a thorough cleaning üòÇ

J
Joe L.
Pure Fisetin

Heard Huberman talk about the benefits of Fisetin supplements on his podcast and hadn't tried them before but after reading more studies I'd recommend anyone over 30 using these.

J
Joe L.
Natural Spermidine

Bought the Spermidine supplements with the Fisetin for maximum senolytic power! Recommend all lognevity enthusiasts to look into the benefits, lots of solid studies out there.

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Meet our Advisors

Dr. Cherry Lo, Ph.D., is a researcher specialising in pathology and immunity, with degrees from CUHK and the University of Hong Kong. Her work focuses on the interaction between NK cells and rheumatoid arthritis, providing new insights into disease mechanisms. As a research scientist, she contributes to advancements in longevity science. With a passion for immunology and translational research, Dr. Lo is dedicated to uncovering innovative solutions for age-related diseases and immune health.

DR. CHERRY LO, Ph.D

Longevity Expert

READ INTERVIEW

Dr. Cherry Lo, Ph.D., is a researcher specialising in pathology and immunity, with degrees from CUHK and the University of Hong Kong. Her work focuses on the interaction between NK cells and rheumatoid arthritis, providing new insights into disease mechanisms. As a research scientist, she contributes to advancements in longevity science. With a passion for immunology and translational research, Dr. Lo is dedicated to uncovering innovative solutions for age-related diseases and immune health.

DR. CHERRY LO, Ph.D

Longevity Expert

Ben is the founder and head grower at one of the UK’s leading fungi farms, where he cultivates a deep passion for mushroom cultivation and education. Since launching his farm in 2022, he has dedicated himself to exploring fungi’s medicinal and ecological potential. Ben is a regular speaker at functional mushroom conferences around the UK where he shares his knowledge and enthusiasm for the fungal kingdom. He aims to inspire others to connect with these fascinating organisms.

BEN GIBSON

Mycology Expert

Ben is the founder and head grower at one of the UK’s leading fungi farms, where he cultivates a deep passion for mushroom cultivation and education. Since launching his farm in 2022, he has dedicated himself to exploring fungi’s medicinal and ecological potential. Ben is a regular speaker at functional mushroom conferences around the UK where he shares his knowledge and enthusiasm for the fungal kingdom. He aims to inspire others to connect with these fascinating organisms.

BEN GIBSON

Mycology Expert

Carolina is a holistic sleep coach specialising in circadian biology, nutritional therapy, and biohacking. With over seven years of experience, she blends scientific research with ancestral wisdom to help clients achieve deep, restorative sleep naturally. Her expertise in light exposure, stress resilience, and nervous system regulation allows her to create personalised, sustainable solutions without reliance on medication. Carolina is passionate about empowering individuals to optimise their sleep and overall well-being through evidence-based, holistic practices.

CAROLINA RAMUSKI

Sleep Expert

Carolina is a holistic sleep coach specialising in circadian biology, nutritional therapy, and biohacking. With over seven years of experience, she blends scientific research with ancestral wisdom to help clients achieve deep, restorative sleep naturally. Her expertise in light exposure, stress resilience, and nervous system regulation allows her to create personalised, sustainable solutions without reliance on medication. Carolina is passionate about empowering individuals to optimise their sleep and overall well-being through evidence-based, holistic practices.

CAROLINA RAMUSKI

Sleep Expert