Clinical evidence
made clear.

Digestible analyses of clinical studies within longevity research, critically assessed and shaped into insights you can implement.

Berberine Patches vs Supplements: Do Berberine Patches Work (and Which Is Best)?
25.02.2026

TMG, Milk Thistle, or NAC? Comparing the Best Supplements for Liver Support
As awareness of liver health rises, more people are seeking effective, research-backed ways to support detoxification and long-term liver function. Among the most talked-about supplements are TMG (Trimethylglycine), Milk Thistle, and NAC (N-Acetyl Cysteine). All three have their place -...

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TMG, Milk Thistle, or NAC? Comparing the Best Supplements for Liver Support

03.10.2025
Spermidine vs Fasting: How to Mimic Calorie Restriction, Autophagy & the Blue Zone Diet for Longevity
As interest in healthy ageing grows, scientists are uncovering nutritional strategies that may replicate some of the powerful effects of Calorie Restriction - one of the most studied interventions for extending lifespan in animals. Among these discoveries is Spermidine, a...

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Spermidine vs Fasting: How to Mimic Calorie Restriction, Autophagy & the Blue Zone Diet for Longevity

03.09.2025
Oral Hyaluronic Acid Supplements for Menopause Symptoms: Benefits and Side Effects
Menopause is a natural phase of a woman’s life but can bring with it a host of uncomfortable symptoms - including vaginal dryness, irritation, and atrophic vaginitis. While topical creams, lubricants, and prescription hormones like estradiol are commonly recommended, a...

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Oral Hyaluronic Acid Supplements for Menopause Symptoms: Benefits and Side Effects

28.08.2025
NMN Injection vs Oral Capsules: Clinical Evidence & Risks Compared
NMN injection is increasingly discussed in longevity clinics and biohacking communities as a faster way to increase NAD+ levels. But is injectable NMN actually more effective than high-purity oral capsules? In this evidence-based guide, we compare safety, bioavailability, cost, regulation...

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NMN Injection vs Oral Capsules: Clinical Evidence & Risks Compared

21.08.2025
Manapura x Dawnstalkers Solstice Swim 2025: A Sunrise Ritual of Resilience, Nature and Neurobiology
On the morning of the summer solstice – 21st June 2025 – as the sun began to rise over the Severn Estuary, something extraordinary took place. At precisely 4:00 am, over a hundred brave swimmers gathered at Penarth seafront, Wales,...

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Manapura x Dawnstalkers Solstice Swim 2025: A Sunrise Ritual of Resilience, Nature and Neurobiology

19.08.2025
Should You Pair NMN with Resveratrol? Benefits, Dosing & How To Take
As the science of longevity evolves, researchers continue to explore compounds that may help extend human healthspan and delay age-associated decline. At the fore front of this research are Nicotinamide Mononucleotide (NMN) and Trans-Resveratrol. Individually, these molecules play vital roles...

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Should You Pair NMN with Resveratrol? Benefits, Dosing & How To Take

18.08.2025
Manapura x The House of KOKO Retreat 2025: A Cathartic Union of Nature, Luxury and Wellness
From 25th to 30th June 2025, the serene countryside of Somerset became the epicentre of transformative wellness, connection, and luxury. The House of KOKO – renowned for its cultural innovation and commitment to elevated living – hosted its iconic Camp...

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Manapura x The House of KOKO Retreat 2025: A Cathartic Union of Nature, Luxury and Wellness

06.08.2025
Berberine & Fisetin: Two Emerging Natural Solutions for PCOS Management
Polycystic Ovary Syndrome (PCOS) is a complex and multifactorial condition affecting up to 1 in 10 women of reproductive age in the UK. Hallmarked by insulin resistance, hormonal imbalances, and chronic low-grade inflammation, PCOS presents significant metabolic and reproductive challenges....

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Berberine & Fisetin: Two Emerging Natural Solutions for PCOS Management

21.07.2025
NMN Outperforms NR in Human Trials: Why Bioavailability Matters
As researchers increasingly explore NAD⁺ precursors, NMN has emerged as more effective than NR (nicotinamide riboside) in human clinical contexts. These compounds are central to cellular energy metabolism and longevity science, but not all NAD⁺ boosters are created equal.

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NMN Outperforms NR in Human Trials: Why Bioavailability Matters

03.07.2025
What is NAD World 3.0?
In the world of cellular health and longevity, few molecules have attracted as much attention as NAD⁺ (nicotinamide adenine dinucleotide). Essential for metabolic function, energy production, and DNA repair, NAD⁺ levels naturally decline with age, contributing to fatigue, slower recovery,...

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What is NAD World 3.0?

01.07.2025

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